In this case, though, the amount of saccharin required to block the receptors that cyclamate activates would have bitter effects on its own. (sciencenews.org)
Except that I drank coffee just before the measurement with artificial sweetener cyclamate. (idmprogram.com)
So it's probably the actions of cyclamate at saccharin's bitter receptors that help block the bitterness, Behrens and his colleagues report September 14 in Cell Chemical Biology. (sciencenews.org)