CNGs open after direct binding of cyclic nucleotides, cAMP, and cGMP. (ptglab.com)
Of particular significance was the development of chemical methods to convert highly polar signalling molecules like cyclic nucleotides, inositol phosphates, and phosphoinositides to membrane - permeant, bioactivatable derivatives («prodrugs»)(Schultz 2003; Laketa et al. 2009, Laketa et al. 2014). (embl.de)
Symposia VI: Nitric Oxide and Sympatho - vagal Regulation Researchers will discuss targeting cyclic nucleotides to rescue cardiac sympatho - vagal phenotypes in cardiovascular disease and the blood brain barrier and control of arterial pressure. (physiologyinfo.org)