(c) Proof of principle experiment with pacCer - labeled cytosolic extract using biotin for derivatization. (biologie.uni-osnabrueck.de)
The process involving liquid chromatography - electrospray ionization - tandem mass spectrometry relies on a vital step called «charge derivatization» or using a permanently charged reagent to selectively trap the estrogens and isolate them from the lipids and proteins that could interfere with estrogen detection, Schug said. (sciencedaily.com)
Girard derivatization for LC - MS / MS profiling of endogenous ecdysteroids in Drosophila. (dresden-ipp.de)