By varying the compositions of lipids, cues, and diffusible factors in the scaffolds, we engineered a very versatile and flexible platform that can be used to amplify specific T cell populations from blood samples, and that could be deployed in existing therapies such as CAR - T cell therapies,» said Mooney, Ph.D., a Core Faculty member at the Wyss Institute and leader of its Immunomaterials Platform. (sciencedaily.com)
One experiment examined the effect of the protein insulin on ADDLs (amyloid - beta derived diffusible ligands), toxic proteins that build up in the brains of Alzheimer's patients, causing cell death. (discovermagazine.com)
By tracking a limited ensemble of diffusible molecules over time, the spatiotemporal dynamics of molecules and the connectivity within microcompartments can be obtained in addition to superresolved (tracking and localization microscopy, TALM). (biologie.uni-osnabrueck.de)