The team found that the levels of mitochondrial DNA, presumably released from dying neurons, were increased in the blood plasma of mice that were starting to develop the symptoms of HD. (sciencedaily.com)
Next, they looked for mutants with shortened life - spans and examined them for signs of dying neurons. (sciencemag.org)
Dr. Steven R. Goodman, Editor - in - Chief of Experimental Biology and Medicine said «D'Mello and colleagues have performed a transcriptomic study, utilizing RNA - Seq, to identify transcripts that are changed in expression in dying neurons. (sciencedaily.com)