"Early lesions" refers to the initial stages or small signs of damage or illness in the body. It refers to the early development of health problems, which can be detected before they become more serious. Full definition
Of note, by 6 months post involution, as few pSTAT5 + cells (5.7 ± 2.2 %) could be detected in early lesions of parous mice, as in virgin mice (p = 0.3; n = 4 mice; data not shown), suggesting that with time, parity - induced elevated levels of pSTAT5 in parous mice subside. (elifesciences.org)
Since pSTAT5 + cells occur at 10-fold higher frequency than pSTAT3 + cells in early lesions from our mouse model (18 % vs 1.8 %), C188 - 9 is effectively a STAT5 inhibitor in this setting. (elifesciences.org)
Apoptosis levels were inversely correlated with levels of pSTAT5 in early lesions from these two groups of mice (Figure 4 — figure supplement 2B). (elifesciences.org)