For example, we have built unique probes for real - time NMR studies of catalysts under operating conditions, single - particle laser ablation mass spectrometers for analysis of aerosol particles, and the nanospray desorption electrospray ionization instrument for highly sensitive analysis of minute samples. (pnnl.gov)
The most broadly useful methods for chemical and biochemical samples use electrospray ionization - mass spectrometry (ESI - MS). (pnnl.gov)
That approach — known as electrospray ionization — ionizes large molecules by dissolving them in a solvent and using an intense electric field to pull tiny charged droplets of solution from the end of a needle. (sciencemag.org)