It is clear, however, that evidence of an excess of amino acid substitutions (at least from site - by - site tests) is no longer a sufficiently convincing demonstration of selection, not only because a high ratio could result from selection on synonymous mutations rather than positive selection on proteins [5], but also because there is potentially a high false discovery rate of selected sites [6]. (journals.plos.org)
In order to control for type 1 error when conducting multiple comparisons, Benjamini and Hochberg's (1995) rough false discovery rate was used and the level of significance was measured at below 0.025. (file.scirp.org)
We employed false discovery rate (FDR) correction to correct for multiple comparisons across brain regions. (nature.com)