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Phrases with «gene fusions»

Gene fusions refer to a genetic event where two different genes join together, forming a new combination. This can happen when pieces of genes break and reattach to different genes or when there are changes in the structure of chromosomes. Gene fusions can lead to alterations in the function or regulation of genes, potentially affecting the development of diseases like cancer. Full definition

Related phrases

Sentences with «gene fusions»

  • In the current study, the CUMC researchers conducted genetic analyses of glioblastomas from nine patients, looking specifically for gene fusions. (newsroom.cumc.columbia.edu)
  • «We look forward to conducting further research through the STARTRK - 2 phase II trial and are hopeful that treatment with entrectinib in patients with a range of advanced or metastatic solid tumors harboring NTRK1 / 2/3, ROS1, or ALK gene fusions will result in very meaningful benefit.» (sciencedaily.com)
  • After a median follow - up of 11 months, 11 of the 13 patients who responded remain on the study, including one patient who had non-small cell lung cancer (NSCLC) with a ROS1 gene fusion who has had a complete response that has been maintained for more than two years. (sciencedaily.com)
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