The effects of mutations and other genetic changes in cancer cells play out in the complex networks of molecular interactions or «signaling pathways» involved in cell growth, proliferation, and other hallmarks of cancer biology. (sciencedaily.com)
This widespread lack of the need for telomerase is used by evolution as a key component of our defense against cancer, because having a limit to the size and renewal of telomeres prevents our cells from replicating themselves indefinitely — the crucial hallmark of cancer. (discovermagazine.com)
You can read the first seven Hallmarks of Cancer articles here. (scientificamerican.com)