Random - bred Hartley strain guinea pigs which do not respond immunologically to conjugates of hapten and poly - L - lysine mere mated with heterozygous guinea pigs which do. (science.sciencemag.org)
To make this work, Janda and his research team designed small molecules called haptens with highly similar structures to the target drugs. (seeker.com)
«Normally the immune system mobilizes a mixture of various white blood cells to attack hapten - exposed tissues,» reports Dr. van den Boorn. (sciencedaily.com)