Devine SM, Hoffman R. Role of mesenchymal stem cells in hematopoietic stem cell transplantation. (cellr4.org)
The discovery could provide insight for using megakaryocyte - derived factors, such as TGF - B1 and FGF1, clinically to facilitate regeneration of hematopoietic stem cells, he adds. (sciencedaily.com)
The team used CRISPR - Cas9 to correct the disease - causing mutation in hematopoietic stem cells — precursor cells that mature into red blood cells — isolated from whole blood of sickle cell patients. (sciencedaily.com)