His group is are studying the mechanism of stable inherited epigenetic transcriptional repression by Polycomb - group (Pc - G) protein complexes, and the effects of deregulation of Pc - G genes on Homeobox gene expression, development, Cell cycle control and cancer formation. (eurosystemproject.eu)
Lim1 belongs to a set of genes, called the homeobox genes, that are essential to embryonic development — and that are present in all animals. (discovermagazine.com)
The scientists also identified four homeobox genes — the kind involved in the development of body structures — which are known to specify the regions of the spine and legs. (sciencedaily.com)