Beclin 1 is the human homolog of BEC - 1, has been shown to be monoallelically deleted in up to 75 % of various human cancers. (sciencedaily.com)
In addition, I'm also interested in investigating the dynamics of archaeal cytoskeletal proteins and structures, honing in on homologs from the Asgard clade which I can express in heterologous systems. (evocyt.com)
Ross Cagan's laboratory at Mount Sinai Hospital in New York City has developed a method to recreate human tumors in Drosophila, which is believed to have functional homologs for some 75 percent of human disease - causing genes. (the-scientist.com)