Sentences with word «homolog»

Beclin 1 is the human homolog of BEC - 1, has been shown to be monoallelically deleted in up to 75 % of various human cancers.

In addition, I'm also interested in investigating the dynamics of archaeal cytoskeletal proteins and structures, honing in on homologs from the Asgard clade which I can express in heterologous systems.

Ross Cagan's laboratory at Mount Sinai Hospital in New York City has developed a method to recreate human tumors in Drosophila, which is believed to have functional homologs for some 75 percent of human disease - causing genes.

Importantly, the composite genomes of Asgard archaea encode homologs of actin genes, actin - binding proteins, multiple ESCRT complex homologues, and tubulin.

Thursday, Oct. 20, 9:30 - 9:45 am, Room 221, West Building Platform Presentation: Mutations in spliceosome - associated protein homolog CWC27 cause autosomal recessive syndromic retinitis pigmentosa M. Xu, Baylor College of Medicine, et al

«This reaction is interesting as close relatives of this protein, known as homologs have also been found in animals — ranging from invertebrates like the horseshoe crab to humans — where they play a role in the defence against bacteria,» continues Künzler.

Like its better - known homolog, Edmodo, Easy Class is a free online classroom cum social networking site cum Learning Management System where you can create classes, add assignments and assessments, etc..

Searches for homologs in the nematode Caenorhabditis elegans yielded only one gene, designated hlh - 1, expressed in body - wall muscle cells and their precursors.

Additionally, we support and expand upon the hypothesis that X inactivation is primarily driven by gene loss on the Y. Using linear discriminant analysis, we show that X-inactivation status can successfully classify 90 % of X-linked genes into those with functional or nonfunctional Y homologs.

Rune Ougland Role of the mammalian AlkB homologs 1 and 3 in RNA repair and epigenetic regulation of stem cell differentiation and development Faculty of Medicine, University of Oslo, 29 March 2012 Supervisor: Arne Klungland

1), sea anemone Boule1 was used as the Boule homolog sequence.

FBJ murine osteosarcoma viral oncogene homolog B, also known as FOSB or FosB, is a protein that, in humans, is encoded by the FOSB gene.

One involves the application of haplotype resolved Hi - C to explore the structure of homolog pairing in Drosophila.

In a paper published by Scientific Reports today, the research team found the activity of this protein, called PTEN (for Phosphatase and tensin homolog deleted on chromosome 10), is different between men and women.

Using this type of material, Jin et al. [10] examined the DNA arrangement along stretched chromatin fibers from individual maize centromeres and found that tracts of the maize centromere repeat element CentC were interspersed with CRM, the maize homolog of CRR, and unknown sequences.

Unfortunately, work combing CRISPR with AAVs for improved genome editing is hampered by the fact that even small Cas9 homologs like SaCas9 and their requisite gRNAs take up essentially all of an AAV's ~ 4.5 kB packaging capacity.

The use of coded PCR primers enables high - throughput sequencing of multiple homolog amplification products by 454 parallel sequencing Binladen, J., M. T. P. Gilbert, J. P. Bollback, F. Panitz et al. 2007.

The use of coded PCR primers enables high - throughput sequencing of multiple homolog amplification products by 454 parallel sequencing.

Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V, Andrews NC, Caput D, McKeon F. p63, a p53 homolog at 3q27 - 29, encodes multiple products with transactivating, death - inducing, and dominant - negative activities.

Suga, H., Katoh, K. & Miyata, T. Sponge homologs of vertebrate protein tyrosine kinases and frequent domain shufflings in the early evolution of animals before the parazoan - eumetazoan split.

We determined the x-ray structure of the human BK Ca2 + gating apparatus at a resolution of 3.0 angstroms and deduced its tetrameric assembly by solving a 6 angstrom resolution structure of a Na + - activated homolog.

No. 5,817,479, entitled Human Kinase Homologs, claims 44 ESTs which are fragments of genes encoding protein kinases.

Analysis of the primary sequence relationships of DMC1 from Saccharomyces cerevisiae and UvsX of T4 relative to the three - dimensional structure of RecA from Escherichia coli suggests that both proteins are structural homologs of bacterial RecA proteins.

Zavolan's group will now investigate whether the mammalian homolog similarly slows aging and extends lifespan by regulating protein synthesis genes in response to nutrients and stress.

EZH1 — or Enhancer of Zeste Homolog 1 — is the scientific name of this gene.

Of the 731 predicted genes on Mmu 16, 509 align with orthologs on the corresponding portions of the human genome, 44 are likely paralogous to these genes, and 164 genes have homologs elsewhere in the human genome; there are 14 genes for which we could find no human counterpart.

Genes in the first group were expressed in many organs; these housekeeping genes have X homologs that escape X inactivation.

Although we were unable to determine the cellular specificity of this response with existing methods, systemic induction of cell death by RNAi knockdown of a BCL - 2 homolog results in large tissue lesions and lysis (Pellettieri et al., 2010).

Some of them acquired additional domains during evolution (e.g. DNA polymerase, mRNA export factor), whereas others show a combination of domain rearrangements and gene duplications (e.g. G - protein coupled receptor homologs, US22 domain proteins), and thus approach the complexity of eukaryotic protein family evolution.