Phrases with «homologous recombination»

Homologous recombination is a process in which DNA molecules exchange portions of their genetic material with each other. It can be thought of as a DNA "swap" between two similar DNA strands. This process plays a crucial role in repairing damaged DNA, creating genetic diversity, and ensuring proper chromosome segregation during cell division. Full definition

Sentences with «homologous recombination»

  • Indeed, at least in part, the abnormalities in homologous recombination deficiency have contributed to the very outstanding responses to platinum therapy and very striking new data with PARP (poly [ADP - ribose] polymerase) inhibitors. (cancernetwork.com)
  • Cancer Network: What are the ways to test for this deficiency of homologous recombination in patients with ovarian cancer? (cancernetwork.com)
  • Caris performed the molecular profiling on 48,733 solid tumor samples to assess the prevalence of homologous recombination deficiency in about 20 different types of solid tumors. (sciencedaily.com)
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