Abundant amyloid plaque deposition is evident throughout all cortical layers, hippocampal formation and amygdala in homozygote transgenic rats. (actaneurocomms.biomedcentral.com)
(In the unlikely case of a female homozygote for hemophilia, whose father would have to be a hemophiliac himself, she would in most cases die during development. (ashgi.org)
The inclusion of homozygotes (possessing two copies of the ridged alleles) would make the observed incidence be less than 25 % when averaged across the population in the study. (en.wikipedia.org)