Immunoprecipitation is a scientific technique used to selectively isolate and collect a specific protein or molecule from a mixture of substances using antibodies. Full definition
Normal rabbit IgG (Millipore) was used to control the nonspecific immunoprecipitation of chromatin by immunoglobulins. (cancerres.aacrjournals.org)
To evaluate histone modification (another epigenetic event), the authors employed chromatin immunoprecipitation with high - throughput sequencing (CHiP - Seq) to capture DNA sequences bound by H3 histones marking active (K4me1, K4me3, K27ac, K36me3) or repressed (K27me3, K9me3) chromatin. (massgenomics.org)
In the study, the team performed a genome - wide chromatin immunoprecipitation analysis for genes that were the target of BMAL1, a core clock component that binds to many other clock genes, regulating their transcription. (sciencedaily.com)