Phrases with «inverse agonists»

Inverse agonists are a type of medication or substance that produces the opposite effect compared to normal. They work by binding to certain receptors in the body and reducing their activity, as opposed to enhancing it like agonists. In simple terms, they do the opposite of what regular medicines do, decreasing the activity of specific receptors rather than increasing it. Full definition

Sentences with «inverse agonists»

  • Antiobesity efficacy of a novel cannabinoid - 1 receptor inverse agonist, N --LSB-(1S, 2 S)-3 -(4 - chlorophenyl)-2 -(3 - cyanophenyl)-1-methylpropyl]-2-methyl-2 --LSB-[5 -(trifluoromethyl) pyridin -2-yl] oxy] propanamide (MK - 0364), in rodents. (researchdiets.com)
  • We report the crystal structure of a human β2 - adrenergic receptor — T4 lysozyme fusion protein bound to the partial inverse agonist carazolol at 2.4 angstrom resolution. (science.sciencemag.org)
  • Following postdoctoral training at the State University of New York, Stony Brook with Masayori Inouye, he joined the Schering - Plough Department of Immunology, where he characterized the biology of a new class of cannabinoid CB2 receptor - specific inverse agonists. (sciencemag.org)
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