Traynelis reports that his clinical colleagues are developing guidelines for physicians on the use of memantine for children with GRIN gene mutations. (emoryhealthsciblog.com)
«One surprise was that many proteins that increased in level with normal learning also increased, although not as much, with treatment with memantine alone,» says Gardiner. (asbmb.org)
In 2003, the FDA approved memantine for moderate - to - severe Alzheimer's disease, but two years later the agency rejected an application from the manufacturer, Forest Laboratories, to expand the approval to mild Alzheimer's. (health.com)