"Mouse macrophages" refers to a type of immune cell found in mice. They are responsible for identifying and engulfing harmful bacteria and viruses in the body to help protect against infections. Full definition
In addition, morpholino antisense inhibition of NAIP5 activity in mouse macrophages from resistant mice resulted in an increase in permissiveness of Legionella replication (J: 129300). (jax.org)
The MGH - based team conducted an RNA - interference - based genome - scale screen of mouse macrophages, selectively knocking down the expression of around 8,000 genes, and found that TREML4 — one of a family of receptors found on granulocytes and monocytes — amplifies the response of innate immune cells to activation via TLR7. (sciencedaily.com)
They show that highly purified NS1 acts as a pathogen - associated molecular pattern (PAMP) that activates mouse macrophages and human peripheral blood mononuclear cells (PBMCs) in culture via TLR4, resulting in release of inflammatory cytokines — an effect that was blocked by either a TLR4 antagonist or an anti-TLR4 antibody. (stm.sciencemag.org)