Neoadjuvant therapy refers to a type of treatment, usually used for cancer, that is given before the main treatment, such as surgery or radiation therapy. It is used to shrink the tumor and make it easier to remove or treat. Full definition
Loibl and colleagues investigated whether the presence of a PIK3CA mutation affected patients enrolled in the GeparSixto (G6) clinical trial in experiencing a pathologic complete response after neoadjuvant therapy. (sciencedaily.com)
In some women with breast cancer treated with neoadjuvant therapy, no residual invasive cancer can be detected in breast tissue samples and lymph nodes removed during surgery. (sciencedaily.com)
«In an era of increasing use of minimally invasive surgery that enables administration of adjuvant therapy more reliably,» says Dr. Yendamuri, «the paradigm of routine neoadjuvant therapy for patients with this stage of disease should be reconsidered.» (roswellpark.org)