"Neoplastic transformation" refers to the process when normal cells in the body undergo changes that cause them to become cancer cells. Full definition
Furthermore, only those fusion - derived IEC - 6 cell clones that had undergone the changes in cellular growth indicative of neoplastic transformation produced tumors in mice. (sciencedaily.com)
«The results provide evidence for another molecular mechanism driving neoplastic transformation — genomic catastrophe.» (sciencedaily.com)
The observations suggest strongly that genomic catastrophe can produce the required and necessary molecular alterations for neoplastic transformation and tumorigenesis in normal founder cells in the absence of selective pressures or ongoing genomic evolution.» (sciencedaily.com)