A screen for mouse genes dependent on dHAND, a transcription factor implicated in neural crest development, identified Ufd1, which maps to human 22q11 and encodes a protein involved in degradation of ubiquitinated proteins. (science.sciencemag.org)
The Pax3 protein, which is encoded by the Pax3 gene, regulates neural tube closure and cardiac neural crest development by blocking the activity of p53, which is a cell - death protein. (joslin.org)
We hope this finding will be useful to researchers studying neural crest development and stem cell differentiation.» (sciencedaily.com)