The UT Southwestern group had previously used CRISPR - Cas9, the original gene - editing system, to correct the Duchenne defect in a mouse model of the disease and in human cells. (sciencedaily.com)
And when sepsis does develop, they are three times more likely to survive than those with the original gene. (sciencemag.org)
That group also concluded that the increased risk of sepsis caused the defective variant to replace the original gene. (sciencemag.org)