Even as he leads a national clinical trial testing a combination of paclitaxel chemotherapy with an experimental agent known as efatutazone, Dr. Smallridge is working with Dr. Copland and researcher Laura Marlow to find an HDAC inhibitor that might offer additional benefit. (sciencedaily.com)
The results from the Moffitt study suggest that TIM -3-targeting drugs may effectively launch an immune response against cancer cells, particularly when combined with paclitaxel in breast cancer patients. (sciencedaily.com)
To uncover how groups of cancer cells achieve functional diversity (through RNA) to survive chemotherapy, Lopez - Diaz dosed dishes of human pre-cancer and metastatic breast cancer cells with the cancer drug paclitaxel for a week and then removed the drug for a few weeks, mimicking the treatment cycle for a cancer patient. (salk.edu)