His lab has also reported that a different signaling factor called phospholipase C - beta3 (PLC - β3) antagonizes mast cell activation by blocking STAT5. (lji.org)
The scientists confirmed that the drug was inhibiting activation of phospholipase Cγ1 in the mice. (sciencedaily.com)
Then, when they infused it into the blood of the mice, pY816 reduced by half the amount of activated phospholipase Cγ1 in the brain. (sciencedaily.com)