Pluripotency means the ability of a cell or organism to develop into many different types of cells or tissues. It refers to the potential for flexibility and versatility in the development and specialization of cells. Full definition
Histone demethylation through JMJD5 is found to be vital for the cell cycle and maintenance of pluripotency in embryonic stem cells (stemcellsportal.com)
(A) Expression of pluripotency markers from iPSCs (HiPSC - 1 control) generated following retroviral transduction of unsorted HUF1 cells. (journals.plos.org)
In the current study, ZFP217 was found to regulate m6A deposition on to mRNAs created by stem cell pluripotency genes by attaching to another enzyme, m6A methyltransferase - like 3 (METTL3), and rendering it inactive. (sciencedaily.com)