In highly proliferative lesions with increased Ki67, estrogen receptor was negative, but human epidermal growth factor receptor 2 was usually positive with a distribution that was similar to that reported for human intraepithelial lesions (7). (cebp.aacrjournals.org)
Phase 2 — Proliferative Phase: In this phase, granulation, contraction, and epithelialization of the injured tissues occurs. (todaysveterinarynurse.com)
The strict limit in proliferative potential of normal human somatic cells - a process known as replicative senescence - is highly relevant to the immune system, because clonal expansion is fundamental to adaptive immunity. (sens.org)