The production of the HIF - 1 inhibitor occurs in response to hypoxia in these cells. (sciencedaily.com)
The findings support the hypothesis that FOP lesions thrive in a hypoxic microenvironment, not simply due to oxygen deprivation, but also because of a maladaptive response to hypoxia by the HIF - 1α molecular alarm, similar to that seen in cancer. (sciencedaily.com)
Insight into the novel role that NMDA receptors play in retinal responses to hypoxia may be derived from study of the coordinated expression patterns of genes that interact, either directly or indirectly, with the NMDA receptor; namely, the NMDA interactome. (molvis.org)