Since completing the initial paper published Thursday, the team has analyzed 50 more samples from eye fluid of retinoblastoma patients, including those with less aggressive tumors whose eyes were saved, to get a start on determining what factors might be at play in tumor progression. (statnews.com)
The cyclin - dependent kinase (CDK) inhibitors p21waf1 and p27kip1 and underphosphorylated retinoblastoma protein levels were up - regulated and cyclin A levels were decreased in a concentration - dependent manner (Fig. 5B and C). (cancerres.aacrjournals.org)
Under the mentorship of Drs. Richard L. Hurwitz and Catherine M. Bollard, he characterized the immune response against an adenoviral vector delivered intravitreally in retinoblastoma patients. (brightfocus.org)