Known as a COX - 2 inhibitor, Bextra belongs to the same class of drugs as rofecoxib (Vioxx), which manufacturer Merck yanked from pharmacy shelves last September after safety risks appeared (SN: 10/30/04, p. 286: Available to subscribers at COX - 2 inhibitor pulled off market.). (sciencenews.org)
In addition to the drug rofecoxib, pharmaceutical companies have reportedly used ghostwriting to market sertraline, olanzapine, gabapentin, estrogen replacement therapy, paroxetine, methylphenidate, milnaciprin, venlafaxine and dexfenfluramine. (legalblogwatch.typepad.com)
Using the example of the pain reliever rofecoxib, which was sold under the brand name Vioxx, and the occurrence of heart attack, the researchers reproduced that known association between the two using the new research method. (sciencedaily.com)