The only way the virus could become resistant to this approach would be to develop several mutations at the same time, which is highly unlikely to happen. (newscientist.com)
A team led by co-senior author David Fitzpatrick, BMBS, at the University of Edinburgh did not find any effects of SMCHD1 mutations in mice, and Talkowski notes that this may reflect the involvement of several mutations in arhinia — similar to the way SMCHD1 mutations contribute to FSHD2 — and that many factors can alter how the conditions are manifested. (sciencedaily.com)
But a comparison of its DNA to that of another human has revealed several mutations in genes involved in bone disorders — and confirmed once and for all that this being is definitely from our world. (sciencemag.org)