By combining large datasets of protein - protein interactions and filtering by brain - specific gene expression in patients with and without Huntington's disease, the scientists narrowed potential interactors to 13 candidates, including 7 that are known targets in Huntington's disease. (sciencedaily.com)
This line of research will reveal how developmental signaling pathways interact with chromatin to establish specific gene expression programs. (dresden-ipp.de)
Sex differences describe biology - linked differences between women and men, which are caused by differences in sex chromosomes, sex - specific gene expression of autosomes, sex hormones, and their effects on organ systems (Figure 1)(1, 3). (academic.oup.com)