It's too soon to ask if this is how it happens in a patient; instead we are asking how do these drugs affect neurons. (kavlifoundation.org)
A separate analysis showed a similar drop in netrin - 1 in affected neurons in rats whose axons from the brain to the spinal cord had been cut. (news.unchealthcare.org)
However, blocking TSP1, 2 and 4 did not affect neuron survival, suggesting that there is some other factor in the UTC cells that promotes cell longevity. (sciencedaily.com)