He previously revealed the existence of spontaneous immune responses in ovarian tumors as well as described how regulatory T cells and tumor blood vessels affect these responses. (cancerresearch.org)
An experimental drug in early development for aggressive brain tumors can cross the blood - brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James). (sciencedaily.com)
They inhibit tumor blood vessel formation (angiogenesis) and tumor cell migration (needed for metastasis). (cancer.gov)