The phrase "untreated patients" refers to people who have a medical condition or illness but have not received any medical care or treatment for it. Full definition
[21] In the recently presented FLAURA study, in which osimertinib was used in untreated patients with advanced EGFR - mutant NSCLC, the HR for systemic disease control and CNS control similarly favored osimertinib over erlotinib or gefitinib, supporting the preclinical data that showed osimertinib's penetration across the BBB and providing support for using this agent in first - line management of EGFR - mutant patients with brain metastases. (cancernetwork.com)
KEYNOTE - 024 investigated the efficacy of pembrolizumab compared to standard of care with platinum - based chemotherapy in untreated patients with advanced NSCLC and high PD - L1 expression (defined as expression in at least 50 % of tumour cells). (sciencedaily.com)
Choueiri and colleagues conducted the phase I trial to test the safety and efficacy of this combination in previously untreated patients with RCC. (cancernetwork.com)