The present study reports the Duffy blood group genotyping in P. vivax malaria patients from four different Brazilian endemic areas, exploring these significant phenotypic associations between blood group variants, as well as polymorphic regions of RBC receptors, with susceptibility or resistance to malaria. (malariajournal.biomedcentral.com)
It was demonstrated in individuals living in a malaria endemic region of Papua New Guinea that Duffy binding protein adherence to RBCs is significantly reduced for erythrocytes of P. vivax malaria patients who carry one Duffy - negative allele [15]. (malariajournal.biomedcentral.com)
The findings are published in PLoS Medicine: Rosanas - Urgell A, Lin E, Manning L, Rarau P, Laman M, et al. (2012) Reduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case - Control Study. (cggh.org)