Sentences with phrase «cancer stem cells»

Scientists have shown that an inflammatory process within the breast itself promotes growth of breast cancer stem cells.

The antibody also shows promise in targeting cancer stems cells and in preventing the growth and spread of ovarian, lung, breast, colon, pancreatic and other cancers.

The science behind these new therapy and treatment approaches concentrates on self - renewing cancer cells — what are commonly referred to as cancer stem cells.

Researchers measure the impact on cancer stem cell metabolism of 3 natural substances, 3 experimental pharmaceuticals and 1 clinical drug.

Some researchers believe eliminating cancer stem cells may be key to controlling cancer.

The trial involves combining standard chemotherapy with a drug that has been found in laboratory studies to attack cancer stem cells.

This includes identifying pancreatic cancer stem cells, the small number of cells within a tumor that fuel its growth and spread.

They used a newly established cell model that enables scientists to isolate cancer stem cells directly from patient tumor.

They were able to block proliferation of several cancer stem cell lines.

Their stem cell - like properties enable them to maintain a pool of cancer stem cells within the tumor, as well as to produce new mature tumor cells.

What it does is give us a target for development of more efficient and cancer stem cell specific therapies to eliminate the cancer.

In the present study, the researchers show that the actual number of cancer stem cells decreases.

These diets may naturally be providing a shotgun approach to cancer prevention by using a wide variety of beneficial compounds to target multiple pathways that cancer stem cells use to survive.

Another view is that tumors can become resistant to therapy by a process called cell fate decision, by which some tumor cells are killed by therapy and others become cancer stem cells.

Such diets provide a broad approach to cancer prevention because they contain many different compounds that can attack the multiple pathways of cancer stem cell survival.

One view is that cancer stem cells inhabit a «niche» that prevents cancer drugs from reaching them.

When the switch does not get turned off, it enables cancer stem cells to grow.

Can any cancer cell form another tumor, or is it only select cancer stem cells that give rise to new cancer cells?

However, scientists disagree on whether the phenomenon of cancer stem cells extends to different kinds of cancer and what is the best way to target them.

Although cancer stem cells have been identified in many different types of cancer, it is becoming increasingly clear that the properties of these cells may vary greatly among the different tumor types.

Breast cancer stem cells exist in two different states and each state plays a role in how cancer spreads, according to an international collaboration of researchers.

This is the only cell therapy in clinical trial phase, which precisely target cancer stem cells.

It has been shown to target breast cancer stem cells, while leaving alone the good stem cells.

The results show that they both have an effect on cancer stem cells.

Ever since, there has been no more doubt about the general existence of cancer stem cells.

Scientists at Penn State University found that two compounds in red and black grapes, resveratrol (which may hold life - extending benefits) and grape seed extract, killed cancer stem cells in a petri dish and in mice.

1) Notch - 1 induces epithelial — mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells:

«Grape - based compounds kill colon cancer stem cells in mice.»

title =» Breast Cancer Stem Cells vs. Broccoli» >!

However, little is known about the specific stem cell - related effects by which ONC201 inhibits cancer stem cells from renewing.

Researchers targeting colorectal cancer stem cells — the root cause of disease, resistance to treatment and relapse — have discovered a mechanism to mimic a virus and potentially trigger an immune response to fight the cancer like an infection.

A small slice of RNA inhibits prostate cancer metastasis by suppressing a surface protein commonly found on prostate cancer stem cells.

Whitehead Institute researchers have determined that in basal breast cancer cells a transcription factor known as ZEB1 is held in a poised state, ready to increase the cells» aggressiveness and enable them to transform into cancer stem cells capable of seeding new tumors throughout the body.

«Zika virus kills brain cancer stem cells: Virus potentially could be used to treat deadly disease.»

According to the recent cancer stem cell theory, metastatic cells are considered to have the typical characteristics of CSCs including self - renewal capability in addition to their invasiveness, and they also need to adapt themselves to the distant organs that have totally different microenvironment from the primary tumors (17, 18).

The multidisciplinary team is comprised of researchers based in Cardiff University's European Cancer Stem Cell Research Institute (ECSCRI) and the School of Pharmacy and Pharmaceutical Sciences.

«What is important is to be able not only t0 target leukemia cells selectively, but also to eradicate cancer stem cells as well,» Fasan says.

Our results can contribute to the development of new drugs against cancer stem cells but, unfortunately, it takes a long time to get from basic research to usable drugs,» says Stina Oredsson.

Together, these signals activate ADAR1, which edits specific RNA in a way that stabilizes a gene that can make cancer stem cells more aggressive.

In normal cells, this is a part of the wound repair process when PGE2 induces tissues stem cells to regrow; in cancer PGE2 ironically induces regrowth of more cancer stem cells in between chemotherapy cycles, Kurtova and Xiao said.

«Novel mechanism controlling lung cancer stem cell growth discovered.»

«Some cells that we call cancer stem cells adopt deadly characteristics where they can travel through the bloodstream to other tissue and form new tumors.

ONC201 may inhibit cancer stem cell self - renewals by altering their gene expression, according to a study published August 2, 2017 in the open - access journal PLOS ONE by Varun Vijay Prabhu from Oncoceutics, Inc., USA and colleagues.

Therefore, even if the bulk of the tumor has been killed after treatment, the pancreatic cancer stem cells remain and will eventually regrow a tumor and may even migrate to a different location in the body to regrow.