Sentences with phrase «cholesterol metabolism»

They state that there is mounting evidence which suggests that a defect in cholesterol metabolism in the brain may play an important role in AD.

Another benefit of cinnamon is for improving cholesterol metabolism.

Secreted by certain brain cells, APOE is known to regulate cholesterol metabolism within the brain and can bind to A-beta peptides, suggesting that the different forms of the protein may affect whether and how toxic A-beta plaques form.

There, he performed gene therapy experiments in a mouse model of a rare genetic disorder of cholesterol metabolism called Niemann - Pick disease type C. «Nobody in my family had ventured outside of Peru.

He succeeded in cloning the receptor of LDL (the low - density lipoprotein receptor), contributing to the reputation of Brown and Goldstein, who in 1985 were awarded the Nobel Prize in Physiology or Medicine for their work on cholesterol metabolism.

«In studying what causes NPC and how it progresses, we learn more about normal cholesterol metabolism,» Ory said.

Neta holds a BS in Biology from MIT, where she studied cholesterol metabolism in a research laboratory.

Genetic screening later revealed that 24 percent of centenarians from Ashkenazi Jewish populations carry a variant in the CETP gene — an enzyme important for cholesterol metabolism — that reduces the level of the protein CETP in the blood and is linked to a lower prevalence of hypertension, cardiovascular disease and memory loss.

The newly developed glucagon / T3 molecule delivered the T3 selectively to the liver and thereby safely improved within a few days cholesterol metabolism in diet - induced obese mice.

The method developed by this team, called individual - particle electron tomography (IPET), had earlier captured the 3 - D structure of a single protein that plays a key role in human cholesterol metabolism.

She received her Ph.D. in Biochemistry from Wake Forest University School of Medicine in 1992, where she performed her graduate research on LDL cholesterol metabolism in the laboratory of Dr Lawrence Rudel.

He joined the Gladstone Institutes as a postdoctoral fellow in 1993 where his early research into proteins involved in cholesterol metabolism led him to the study of embryonic stem cells and differentiation.

Recently, scientists also found that CoQ10 can help lower unhealthy levels of oxidized LDL cholesterol by modulating gene signals involved with cholesterol metabolism.

Magnesium also has been researched to help optimize HDL cholesterol metabolism, and to support healthy blood pressure levels within the normal range.

It may be a result of the ingestion of soy inhibiting the absorption of cholesterol or the effect of nonprotein components, such as fiber and isoflavones, affecting cholesterol metabolism.

Besides removing heavy metals, calcium EDTA helps with calcium and cholesterol metabolism by removing the toxins, which also prevents free radical damage.

It has been suggested that a high serum cholesterol level is a risk factor for (AD), and that some polymorphisms of genes encoding proteins regulating cholesterol metabolism are associated with AD development.

A bitter fight involving the National Institutes of Health (NIH), two companies, and opposing camps of researchers and parents is marring the emergence of a promising therapy for children with a rare, inherited, and uniformly fatal disorder of cholesterol metabolism.

«Mice don't get atherosclerosis unless their normal cholesterol metabolism is changed,» notes Christian Rask - Madsen, M.D., Ph.D., a research associate in the Nunnally Hoppes lab and lead author on the paper.

Scientific research has vindicated dietary cholesterol, finding that eating cholesterol has no real impact on cholesterol metabolism.

The research stated that there is mounting evidence which suggests that a defect in cholesterol metabolism in the brain may play an important role in Alzheimer's Disease.

I am not really all that concerned because my PhD is in Cholesterol Metabolism and I have no other risk factors (except maybe a bit too much stress!)

Background: Earlier studies have suggested that infant feeding may program long - term changes in cholesterol metabolism.

In 2000, 9 years and three postdocs later, Wellington earned a position as assistant professor at the University of British Columbia, where she studies genes that regulate cholesterol metabolism and examines their role in neurodegenerative diseases such as Alzheimer's.

On a high - fat diet, these animals quickly develop plaques in their arteries because they lack a gene that regulates cholesterol metabolism.

Using a genetic screen, VanderVen and his team identified genes involved in cholesterol metabolism.

Liu et al. (45) demonstrated that the hepatic effects of WBV were correlated with reductions in sterol regulatory element binding protein 1c (SREBP1c), a transcription factor that regulates genes involved in cholesterol metabolism (50).

Recently, thanks to major advances in human genetics, it has become increasingly clear that not only APOE and cholesterol metabolism, but also the proper functioning of microglial cells, strongly modulates the risk of developing AD in old age.

We believe that our project will underscore novel molecular insights related to the association between the cholesterol metabolism and Aβ accumulation in the brain.

The importance of APOE (a gene involved in cholesterol metabolism) has long been recognized in AD.

Beta cell biology and diabetes, Adipogenesis and obesity, Lipids and cholesterol metabolism, Cardiovascular biology (including atherosclerosis, hypertension, cardiac metabolism, and vascular dynamics), Immunometabolism, Bone homeostasis, Aging and stress response, Cancer metabolism, Mitochondrial biology, Neuronal control of metabolism, Circadian biology

Dr. Bersot's work focuses on genetic disorders of cholesterol metabolism.

Moore's lab researches the mechanisms that underlie imbalances in metabolism as it relates to atherosclerosis and obesity, including noncoding RNA's regulating role in cholesterol metabolism and inflammation.

Drugs that reduce cholesterol levels in the cardiovascular system can strongly benefit people with diabetes or related conditions, but cholesterol in the blood generally can't cross into the brain, and cholesterol metabolism is quite different in the brain, she points out.

He and his long - time colleague, Dr. Michael S. Brown, have worked together for the last 30 years on the genetics and regulation of cholesterol metabolism.

Dr. Mahley is an internationally known expert on heart disease, cholesterol metabolism and, more recently, Alzheimer's disease.

Their discovery of the LDL receptor as the major molecule regulating cholesterol metabolism and its genetic disruption in the human disease familial hypercholesterolemia have been recognized by their receipt of numerous awards, including the Nobel Prize in Physiology or Medicine (1985), the Albert D. Lasker Award in Basic Medical Research (1985), and the U.S. National Medal of Science (1988).

The main mechanisms of action of phytochemicals are: antioxidant activities, modulation of detoxification enzymes, decreasing of platelet aggregation, alterations in cholesterol metabolism, control of concentrations of steroid hormones and endocrine metabolism, reduction of blood pressure, and antibacterial and antiviral activities.

Chromium also has been researched for its role in helping to regulate fat and cholesterol metabolism.

Genes have been found to regulate lipid and cholesterol metabolism, while metabolic markers, such as blood sugar and insulin, are already cemented in science.

Intestinal short - chain fatty acids show health benefits on immune function, as well as on lipid and cholesterol metabolism.

The goal is to make sure your cholesterol metabolism is running smoothly.