Sentences with word «choroid»

Sanford Research scientists are published in Nature Cell Biology for their work developing a model to explore therapies for a pediatric brain tumor known as choroid plexus carcinoma.

This infolding put the photoreceptors in close proximity to the retinal pigment epithelium, enabling the biochemical recycling of retinoids following light absorption, the attenuation of light that passes through the photoreceptors unabsorbed, and the delivery of oxygen and nutrients from the overlying choroid tissue.

When stem cells from the old brain are cultured with signals of a young choroid plexus they can divide and form new neurons (red).

«Unexpected link between choroid plexus, chronic pain.»

Because Sonic Hedgehog might be an indicator of tumor growth, targeting this protein could be clinically beneficial for choroid plexus carcinoma treatment.

«One reason is that signals in the old choroid plexus are different.

Haotian Zhao, Ph.D., is the lead author on the study titled «Sonic Hedgehog promotes proliferation of Notch - dependent monociliated choroid plexus tumour cells.»

The antiserum demonstrates strongly positive labeling of rat choroid plexus and hippocampus using indirect immunofluorescent and biotin / avidin - HRP techniques.

The abnormal features seem to disappear or lessen due to pigment changes and masking of the thin choroid areas.

The medical terms are horrible: osteochondrosis of the medial humeral condyle or ununited anconeal process, fragmented medial choroid process.

The defect may cause an underdeveloped choroid (the blood vessels in the tissue under the retina), defect in the optic nerve, thinning of the sclera, and retinal detachment.

When working to understand eye issues, it's important to understand that the iris, ciliary body, and choroid make up the uvea, which is the middle layer of the eye.

Our study suggests otherwise, though, as we found that a certain type of B cell is quite abundant in the ventricles, meninges, and choroid plexus in the brains of young mice.

Besides the dorsal cortex, researchers were able to grow, among other regions, parts of the ventral forebrain, which makes neurons that connect to the cortex, and the choroid plexus, which generates spinal fluid.

Practical Handbook of OCT (Retina, Choroid, Glaucoma).

Uveal melanoma is a cancer of the iris, ciliary body, or choroid — structures in the eye collectively known as the uvea.

Prof. Fiona Doetsch's research team at the Biozentrum, University of Basel, has discovered that the choroid plexus, a largely ignored structure in the brain that produces the cerebrospinal fluid, is an important regulator of adult neural stem cells.

The scientists measured the volume of the choroid plexus from 3 - tesla structural magnetic resonance images.

«We can imagine the choroid plexus as a watering can that provides signals to the stem cells.

«However, in clinical neuroscience, the functions of choroid plexus beyond cerebrospinal fluid generation have been largely neglected; for example, the size of the choroid plexus is not quantified in routine brain scans,» explains Professor Riitta Hari, who was in charge of the research.

Fiona Doetsch's group uncovered that the choroid plexus secretes a wide variety of important signaling factors in the CSF, which are important for stem cell regulation throughout life.

The cells of the choroid plexus are unusual because they contain multiple primary cilia, hair - like projections from the cell that are important for detecting changes in their environment, signaling through a protein called Sonic Hedgehog.

The CSF is produced by the choroid plexus.

«As the choroid plexus is known to mediate the interaction between inflammation in the periphery of the body and in the brain, it is an interesting and important target for future research of chronic pain and CRPS in particular,» continues Hari.

The dots in the graph show the volume of the choroid plexus in patients with CRPS (on the left) and healthy control subjects (on the right).

«When studying magnetic resonance images of the brains of patients suffering from CRPS, we noticed that the choroid plexus was nearly one - fifth larger in patients than in healthy control subjects,» says Postdoctoral Researcher Guangyu Zhou from Aalto University Department of Neuroscience and Biomedical Engineering (NBE), who analysed the images.

Aalto University neuroscientists, in collaboration with researchers at Helsinki University Hospital and Harvard Medical School, have found a novel connection between the size of the choroid plexus in the brain and complex regional pain syndrome (CRPS).

The volume of the choroid plexus was measured in this work.

The study recently published in «Cell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavior.

The research team led by Prof. Fiona Doetsch at the Biozentrum of the University of Basel has now shown that the choroid plexus is a key component of the stem cell niche, whose properties change throughout life and affect stem cell behavior.

Located in the walls of the brain ventricles, the choroid plexus is best known for producing cerebrospinal fluid, which forms a protective mechanical cushion and immunological buffer for the brain.

In the future, the research team plans to investigate the composition of the signaling factors secreted by the choroid plexus, as well as how these change in different states and affect neural stem cells.

Zhao and his team created an animal model that forms tumors in a part of the brain known as the choroid plexus.

The choroid plexus located in the brain ventricle is marked with red in the brain image.

For example, all the organoids they made appeared to contain parts of the cortex, about 70 per cent contained a choroid plexus — which produces spinal fluid — and about 10 per cent contained retinal tissue.

«Loss of essential protein in the choroid plexus epithelium linked to hydrocephalus.»

Yvan Campos, associate scientist in the St. Jude Department of Genetics and the paper's first author, was instrumental in defining Alix's precise role in the brain's choroid plexus and linking that role to disease.

We were intrigued by the occurrence of hydrocephalus in the brains of these mice and began to investigate the structures within the brain that might be involved — the choroid plexus and the ciliated ependyma,» said corresponding author Alessandra d'Azzo, Ph.D., who holds the Jewelers For Children Endowed Chair in Genetics and Gene Therapy at St. Jude.

Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier.

The epithelial barrier in the choroid plexus of the brain is the blood - cerebrospinal fluid interface.

In the late 1800s, when doctors first began looking into eyes with ophthalmoscopes, they believed that the drusen they observed represented some type of infection, or at least inflammation, of the choroid.

The layer farthest from the incoming light is a rich network of blood vessels known as the choroid.

«We made extensive use of state - of - the art, high - resolution imaging techniques to visualize the impact of Alix deficiency on the overall organization of the choroid plexus epithelium,» said Campos.

In most cases, hypoxia is caused by either a dysfunction of the retinal vasculature, as in diabetic retinopathy and retinal artery and vein occlusions, or it is due to a mismatch between nutrient supply and demand, as in the case of a retinal detachment, where the retina is separated too far from the choroid to receive sufficient oxygen.

All patients were diagnosed with UM from the choroid and / or ciliary body.

The choroid, which is a thin pigmented layer that covers the eyeball.

They were located between the Bruch's membrane and the RPE, and in the choroid.

To displace delicate tissues and folds of the brain — and limit intraoperative damage — a tubular retractor was advanced along the chosen trajectory into the atrium of the lateral ventricle, entering the thalamus at a point identified by the microscope and pointer as superior and lateral to the choroid plexus.