Sentences with phrase «complementary sequence»

With relatively straightforward bio-informatics approaches, it was possible to cross-reference expressed miRNAs with complementary sequences of mRNA tags.

Complementary sequences of miR7 to mammalian KLF4 3 ′ - UTR are shaded red.

MicroRNAs are short RNA molecules that typically bind to complementary sequences in messenger RNAs, thereby controlling the amounts of specific proteins produced by cells.

Running their computer algorithm, the biologists found that 5300 genes contained complementary sequences to an miRNA — suggesting that the miRNA could control that gene's expression, they report in the 14 January Cell.

These customized RNAs include complementary sequences that are tailored to match up with specific DNA sequences in the microbe's genome.

Complementary sequencing using long - read technology will later be performed for regions of high medical importance.

These small RNAs can be used to inhibit gene expression by targeting mRNAs with complementary sequences.

Small RNA molecules can bind to and blunt expression of DNA stretches with a complementary sequence.

But with the RNAs that condense into the same droplet, their complementary sequences are really exposed, so they can find each other and base pair to make a higher - order interaction,» Gladfelter says.

It is composed of a single strand of DNA that binds to a complementary sequence in target DNA.

MicroRNAs are short bits of nucleic acid — the material of DNA and RNA — that can bind to messenger RNAs that code for protein because they have a complementary sequence of A, U, C and G.

Instead, a microRNA can bind to a target RNA strand with a complementary sequence, similar to how two strands of «matched» DNA pair up, and prevent that RNA from getting made into a protein.

The Cas9 enzyme is guided to its genomic target sequence by a small guide RNA with a complementary sequence.

In one experiment, they encoded the same sequence on all the octahedron's tethers, and attached strands with a complementary sequence to gold nanoparticles.

As they report in two new studies, the pair and their colleagues constructed viral vectors, each one containing an RNA molecule designed to shut down a gene with a complementary sequence.

Four probes were used: the «universal» eubacterial probes EUB338 (5 ′ - GCT GCC TCC CGT AGG AGT - 3 ′), EUB338 - II (5 ′ - GCA GCC ACC CGT AGG TGT - 3 ′), EUB338 - III (5 ′ - GCT GCC ACC CGT AGG TGT - 3 ′) and the «non-sense probe» NONEUB (5 ′ - ACT CCT ACG GGA GGC AGC - 3 ′), which has the complementary sequence to EUB338, used to determine non-specific binding of EUB338.

Basically it involves delivering small, 20 - base pieces of double - stranded RNA into a cell that, once inside, will anneal to pieces of RNA that have complementary sequences.