Sentences with phrase «death receptor»

PD - 1, which stands for programmed death receptor - 1, was identified by Tasuku Honjo, M.D., Ph.D., of Kyoto University School of Medicine.

Many receptors in this family, including CD95 are called Death Receptors because of their ability to induce apoptosis2.

The Max Planck researchers then showed that less necroptosis of endothelial cells and less metastasis occur in genetically modified animals in which Death Receptor 6 is disabled.

Firstly, we determined that the mesenchymal subpopulation of HMLEs was not only resistant towards various chemotherapeutics, but also to death receptors such as TNFalpha or Trail.

TRAIL is a proapoptotic member of the TNF family, which induces apoptosis by binding to the cell death receptors DR4 and DR5 (29).

The RIPK family of proteins are actively involved in numerous cell - death processes beyond death receptor — dependent cell death (Vanden Berghe et al., 2016).

When the study authors treated mice with a combination of antibodies against galectin - 9 and the «checkpoint» protein, programmed death receptor 1, or PD1, they found that tumors were less than half the size of those treated with either antibody alone.

The scientists also found that endothelial cells themselves give the signal for their own death: To do this, the vascular wall cells have a receptor molecule called Death Receptor 6 (DR6) on their surface.

The researchers have found that axons receive the message to die as a chemical signal via a cell surface receptor known as «death receptor 6.»

Ewing's sarcoma family tumors are sensitive to tumor necrosis factor - related apoptosis - inducing ligand and express death receptor 4 and death receptor 5

Response of Varicella Zoster specific T cells to Programmed Death Receptor - 1 blockade.