Sentences with phrase «embryonic state»

The ultimate goal of our laboratory is to generate ES - like cells directly from somatic cells by nuclear reprogramming... which converts adult cells back into embryonic state.

In comparison with the cells obtained with the technique developed by Yamanaka, the stem cells obtained by CNIO therefore represent an even earlier embryonic state, with greater capacity for differentiation.

Wearables that attach to the skin, such as MC10's Biostamp, are also part of this category — though they're in a «more embryonic state» and require a much larger shift in consumer habits than a smart watch, Juniper says.

By analysing the early steps that precede tumor formation, Alexandra Van Keymeulen and colleagues found that expression of oncogenic Pik3ca reactivates a multilineage differentiation program in adult stem cells that resembles to an immature embryonic state.

In essence, these studies suggested that a newly fertilized, enucleated egg has the ability to «reprogram» a much older donor nucleus, making the resultant cell behave as though it were at a very early embryonic state.

Now we see that it it is still in an embryonic state.

It is apparent that the thought which developed later of a great day coming which could bring the joy of God's favor to the righteous and stern judgment on the unrighteous is here in an embryonic state.

Reprogramming the skin cells of adult identical twins to their embryonic state eliminated most of these differences, the researchers found when they studied cells from three sets of twins.

The egg cell must then reprogram the nucleus's DNA, basically stripping the body cell of its identity and returning it to an embryonic state.

For the first time, biologists have reprogrammed adult mouse cells back to an embryonic state without using viruses that leave dangerous copies of cancer - causing genes in the cells» chromosomes.

Then his team turned to liver cells, which seemed from previous reprogramming experiments to be easier to send back to an embryonic state.

He investigated whether turning on Oct4, a gene suspected of being involved in cellular reprogramming, could reprogram adult cells back into their embryonic state.

To create them, the skin cells need to be reprogrammed to an embryonic state by exposing them to extra amounts of four critical gene switches.

This year they succeeded in generating mini-livers, or liver buds, from stem cells that were taken from human skin and reprogrammed to an embryonic state.

Jeanne Lawrence at the University of Massachusetts Medical School in Worcester took skin cells from men with the condition and «rewound» them into an embryonic state.

The combined therapy is assuming even greater power as scientists manipulate genes to wind ordinary cells back to an embryonic state.

The observations add weight to the theory that transforming an adult cell's DNA into an embryonic state is a gradual reprogramming process, Hochedlinger says.

The disease model, described in a new study by a UC San Francisco - led team, involves taking skin cells from patients with the bone disease, reprogramming them in a lab dish to their embryonic state, and deriving stem cells from them.

These factors guide a reprogramming process that reverts the cells to an embryonic state, in which they have the potential to become virtually any type of cell.

The process involves reverting cells to an embryonic state.

The ability to easily reprogram any cell to an embryonic state will inevitably bring out maverick human cloners.

One of the greatest came in November 2007, when scientists in Japan and the United States reported that they could make adult skin cells from mice revert to the embryonic state.

The cells were reverted to the embryonic state and then retrofitted with healthy genes lacking the Fanconi mutation.

They propose that normal tissue becomes primed for cancer when oncogenes are activated and tumor suppressor genes are silenced or lost, but that cancer develops only when a cell in the tissue reverts to a more primitive, embryonic state and starts dividing.

The remarkable discovery that it is possible to turn skin cells back to an embryonic state, when they have the potential to become any type of cell in the body, could open up a huge range of possibilities.

Both studies hinge on the concept of nuclear reprogramming, or removing the molecular changes that keep adult DNA from returning to the embryonic state.

We're continuing this work, but with less urgency since the discovery of induced pluripotent stem cells, or iPS cells — adult cells that have been reprogrammed back to an embryonic state.

Shinya Yamanaka discovered how to revert adult cells to an embryonic state.

In two cases, according to the study, the hijacked eggs grew into early - stage embryos that yielded embryonic stem cell lines, indicating that the hosts successfully reprogrammed the skin cell DNA into an embryonic state.

There were factors in the egg that could take adult cells backwards in time and restore them to an embryonic state.

I thought, at least in theory, we should be able to reprogram somatic cells back into the embryonic state so we can make ES - like stem cells directly from skin or blood cells.

«Some of us now think that a memory may return to its embryonic state when it's activated.»

How this galaxy remained in an embryonic state for almost the entire history of the universe is unknown.

Something about the environment of the egg again turned on all of the genes in what had been a differentiated nucleus, reprogramming the adult DNA to its embryonic state, and the newly pluripotent cell was able to grow into a tadpole.

A previous study had reported that, epigenetically, some iPSCs appear to have a negative age, corresponding to an embryonic state.

And as that work started to come up, the question is: Do you really have to back up and go back to an embryonic state, or could you just take a cocktail of cells and put them - a cocktail of factors, put them in and actually direct them to the tissue that you want?

In the original experiment, the researchers took fibroblasts from the tail of this mouse and infected them with a special virus containing four genes (Oct4, Sox2, c - myc, and Klf4) capable of converting the cells to an embryonic state.

Like hundreds of other stem - cell scientists, they had been intrigued and energized by the 2007 discovery that adult cells can be regressed back to an embryonic state simply by inserting four genes into them.

And so this directly puts the paths in place to get you to the lodge as quickly as possible, and in the case of reprogramming all the way back to an embryonic state, it may still work fine to go back up to the top of the hill and eventually find yourself to the lodge, but it's probably much more efficient to do this directly, and a lot less changes will happen along the way.

Dr. ZON: Well, the advantage of this is that you don't really know exactly what paths you are taking when you back the cell up all the way to an embryonic state.

Novel Technique Reverts Cell to Embryonic State The same team of scientists who in 2011 transformed human blood cells into beating heart cells has now developed a safe and super efficient method to turn the clock back on blood cells, reverting them to the primitive state from which they derived.

But it would allow so - called therapeutic cloning in which a patient's cells are coaxed to an embryonic state where they regain the potential to create all of the body's different tissue types.

Thomson was recently deemed one of Time magazine's 2008 Top 100 people for his involvement in reverting adult stem cells to their embryonic state.

Now, scientists at the Salk Institute have found that intermittent expression of genes normally associated with an embryonic state can reverse the hallmarks of old age.

This advance established that cells retain all of their genes as they specialize and that fully developed cells can be re-set to an embryonic state — controversial discoveries at the time.

In both the Untitled series and the No - things series, he tries to capture a snapshot of things before they are formed, still in an embryonic state of meaning.

Although still in an embryonic state, the fact Bitcoin is now being recognised as a legitimate way to improve bank transfers is a sign that it's now becoming a mainstream product.