Sentences with word «enteroendocrine»

Human intestinal organoids (HIOs) generated in the hydrogel matrix differentiate into mature intestinal tissue and present specialized human intestinal cell types, such as enteroendocrine cells (CHGA; red), after transplantation into an animal.

Along with intestinal stem cells, the team identified differentiated nutrient - digesting and absorbing enterocytes, mucus - producing Goblet cells, hormone - secreting enteroendocrine cells, and microbiome - regulating and sensing Paneth cells, and they performed a series of assays that confirmed their functions.

During observation and analysis of the now in vivo organoids, study authors looked for signs of posterior region enteroendocrine cells, which make hormones found in naturally developed human colon.

In addition, the data showed that the gut's hormone - producing enteroendocrine cells (EECs)-- long divided into subsets based on the idea that each only expressed a single hormone — can actually express multiple hormones at once.

The nontumoral mucosa is devoid of labeling, with the exception of rare enteroendocrine and CD11b - positive cells.

Peptides derived from dolicholin, a phaseolin - like protein in country beans (Dolichos lablab), potently stimulate cholecystokinin secretion from enteroendocrine STC - 1 cells

Recent studies using animal and human cell lines and knockout mice have shown that low - energy sweeteners can stimulate intestinal enteroendocrine cells to release glucagon - like peptide - 1 and glucose - dependent insulinotropic peptide.

A combination of in vitro, in situ, molecular biology and clinical studies has formed the basis of our knowledge about the taste receptor proteins in the glucose - sensing enteroendocrine cells and the secretion of incretins by these cells.

ImmunoStar's GLP2R Antibody ensures highly specific staining of neurons in the hypothalamus, brain stem, pancreatic α - cells, enteroendocrine cells in the intestine, as well as enteric neurons, and vagal sensory neurons.

Founded in 2015 after six years of work as part of the Enteroendocrine Discovery Performance Unit of GlaxoSmithKline, Phoundry Pharmaceuticals has created a portfolio of optimized peptides in various therapeutic categories, most notably diabetes and obesity.

All of the cell types in the gut — enterocytes, goblet cells, enteroendocrine cells and Paneth cells — are derived from a type of stem cell that resides within the intestine.

Enteroendocrine cells of the intestine produce a variety of hormones that are secreted upon nutrient intake, such as GLP - 1 (glucagon - like peptide 1) and GIP [232].

For example, intestinal stem cells (ISCs) of the adult Drosophila midgut (Ohlstein and Spradling, 2006; Micchelli and Perrimon, 2006) generate the two major differentiated cell types of the gut, enterocytes and enteroendocrine cells, throughout life.

'' Gut microbiota composition,» Increased intestinal permeability,» Imbalance in the enteroendocrine system, and» Perturbed immune system in the gut.

The present review explores the interactions between sweeteners and enteroendocrine cells, and consequences for glucose absorption and insulin release.