Sentences with phrase «first clinical trial»

On the other hand, first clinical trials with drugs designed to target cancer stem cells are now under way, so far yielding moderately positive results.

Approval for our trial demonstrated that regulatory agencies are amenable to this type of therapy, and enabled us to start a trial in 2017 for our lead therapy, CYP - 001, in the indication of graft vs. host disease, which marks the world's first clinical trial of allogenic iPSC - derived MSCs.

«The long awaited first clinical trial for a drug to treat MHE is now a reality.

«First clinical trial on HER -2-negative breast cancer with nintedanib shows promising results.»

Balkwill's first clinical trial starts later this year, based on developments in her laboratory.

A Japan Ministry of Health, Labour and Welfare panel has accepted a plan to carry out what would be the world's first clinical trials involving induced pluripotent stem (iPS) cells.

Turnstone's first clinical trial with MG1 - MAGEA3, which is still ongoing, is testing the agent as a monotherapy in NSCLC, as well as in breast and esophageal cancers.

A U.S. - based company has received permission to start Europe's first clinical trial involving human embryonic stem (hES) cells.

But CNBC has learned that the first clinical trial study commissioned by HVMN (pronounced «human») found that one of its best - selling supplements was less effective in many ways than a cup of coffee.

The group's first clinical trial, undertaken with Thrive Global, the behavioral change and wellness company founded by Brainstorm Health co-chair Arianna Huffington, begins in May.

The hospital opened in 1913 to treat tuberculosis patients and was the site of the first clinical trials for the hydrazides treatment that eventually led to the cure of the disease, according to the EDC.

«Cancer Research UK scientists first discovered abiraterone and subsequently played a key role in its development, including funding the first clinical trials.

Starting in January, 20 - week - old fetuses with brittle bone disease will be given transplants of stem cells in the first clinical trial of its kind

The new enterprise has just completed its first clinical trials in Germany.

The first clinical trial to deploy CRISPR is now underway in China, and a U.S. trial is slated to start next year.

First clinical trials with a Sclerostin - inhibiting antibody developed by the companies Amgen and UCB showed promising results in that the bone mass of participants suffering from osteoporosis increased.

Last year, Robin Carhart - Harris of Imperial College London and his colleagues conducted the first clinical trial of using psilocybin to treat depression, and got some encouraging results.

The first clinical trial of a drug intended to delay the onset of symptoms of Huntington disease (HD) reveals that high - dose treatment with the nutritional supplement creatine was safe and well tolerated by most study participants.

Researchers are designing the first clinical trials of stem cell treatments for fetuses afflicted with rare bone and blood diseases.

From a tiny, underfunded clinic in Glasgow, Scotland, he set up one of the first clinical trials of estrogen replacement therapy for bone loss in postmenopausal women.

In my experience, this marks both the first clinical trial of an approved drug with an effect on survival in advanced melanoma in the adjuvant setting, and, in this same setting, the first to study an immune checkpoint inhibitor in the adjuvant setting.

With proof of efficacy now published in monkeys and rabbits, preparations are being made for the first clinical trial in humans.

In the next year or so, Coyle expects the first clinical trials from CTIs to start, with three to five candidate proteins identified for trials each year, starting in 2013.

«It's the first clinical trial of a drug with this action in patients with cancer,» says Peter Lewis, the director of research and development.

In the first clinical trial directly comparing three drugs most commonly used to treat diabetic macular edema, researchers found all were effective in improving vision and preventing vision loss.

This is the first clinical trial to be approved by the U.S. Food and Drug Administration (FDA) for matrix therapy of the heart.

A separate group of researchers, also at Boehringer Ingelheim, completed their first clinical trials to explore flibanserin as a libido - enhancer in 2008.

The FDA recently approved the first clinical trial of a human neural stem cell therapy, developed by StemCells, a company in Palo Alto, California, to slow the progress of a fatal childhood neurodegenerative disorder called Batten disease.

«Our study is the first clinical trial to find resveratrol significantly lowers PCOS patients» levels of testosterone as well as dehydroepiandrosterone sulfate (DHEAS), another hormone that the body can convert into testosterone,» said the study's senior author, Antoni J. Duleba, MD, of the University of California, San Diego in La Jolla, CA.

On the basis of the results, insurers agreed to pay for the drug in six more Dutch patients, and Vertex is following up with the first clinical trial of ivacaftor in CF patients with rare mutations.

The project is funded by a European Union grant of approximately six million Euros, with the first clinical trials expected to start in the next 18 months.

The latest study builds off of work Kawai and his colleagues began fourteen years ago, when they launched the first clinical trial that attempted to use bone marrow to induce immune tolerance for kidney recipients, to avoid the sometimes dangerous side effects of life - long immosuppressive therapy.

This was the situation for the 14 arm amputees who took part in the first clinical trial of a new treatment, invented by Chalmers researcher Max Ortiz Catalan, and further developed with his multidisciplinary team in the past years.

Dr. Petersen was involved in the development of the first clinical trial for mild cognitive impairment and continues as a worldwide leader researching this stage of disease when symptoms possibly could be stopped or reversed.

The 11 patients who participated in Retina Implant's first clinical trial, which began in 2005, saw marked improvements in their abilities to read and recognize objects and outlines.

This week, Gordon co-authors a publication that describes the first clinical trial of a drug for progeria.

This will mark the start of the first clinical trial in China using human embryonic stem (ES) cells, and the first one worldwide aimed at treating Parkinson's disease using ES cells from fertilized embryos.

The experiments will also represent the first clinical trials of ES cells under regulations that China adopted in 2015, in an attempt to ensure the ethical and safe use of stem cells in the clinic.

«This is the first clinical trial to assess the impact of a mitochondrial - specific antioxidant on vascular function in humans,» said lead author Matthew Rossman, a postdoctoral researcher in the department of integrative physiology.

Canadian researchers have published promising results of the first clinical trial in the world of a genetically - enhanced stem cell therapy for pulmonary arterial hypertension (PAH).

Pharmaceutical immunoproteasome inhibitors, which are presently tested in a first clinical trial, might allow us to fight autoimmune diseases and prevent the chronic rejection of transplant organs without compromising the patients» entire immune system.

Dr. Stewart is also leading the first clinical trial in the world of a genetically - enhanced stem cell therapy for heart attack.

Nir Barzilai is planning the first clinical trial of a drug that could slow the body's deterioration

In collaboration with the Parker Institute for Cancer Immunotherapy (PICI), the first clinical trial is expected to launch later this year.

The first clinical trials of drug treatments are already under way.

Inspired by such findings, a startup company has launched the first clinical trial in the United States to test the antiaging benefits of young blood in relatively healthy people.

«This is one of the first clinical trials testing an immune checkpoint inhibitor in glioblastoma,» says Rixe.

It has taken more than five years of graft, but at long last approval has been given for the first clinical trial using human embryonic stem cells (hESCs).

The first clinical trial of a drug to block vasculogenic mimicry — and thus potentially limit tumor growth — has begun in the United States and Taiwan.