Sentences with phrase «glucose transport»
"Glucose transport" refers to the movement of a sugar called glucose from one place to another in the body. Glucose, which comes from the food we eat, is an important source of energy for our cells. The phrase describes how glucose is transported or moved through the bloodstream to be delivered to the different parts of the body where it is needed. Full definition
Vitamin D may also directly stimulate the expression of the insulin receptor, thereby improving glucose transport in human cells (54).
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T3 stimulates glucose transport into cells, and transport is the limiting factor in glucose utilization in many cell types.
Insulin assists amino acid and glucose transport into muscle cells.
It also regulates glucose transport, at the cell membrane level, which makes it useful for those with insulin sensitivity.
Furthermore, the model has been used to study the molecular background for the impaired glucose transport and glycogen synthesis associated with insulin resistance in skeletal muscles.
The chemicals may contribute to diabetes by altering insulin production, disrupting related genes or changing glucose transport or fat metabolism, according to scientists.
The overweight or obese individuals however had a significant increase of glucose transport into cells and over-expression of fat - producing genes, in comparison to fat biopsy samples from those individuals not consuming low - calorie sweeteners.
Acute insulin stimulation increased glucose transport in type 2 cultures to corresponding values at insulin concentrations of 1 pmol / l and 1 nmol / l, but it decreased in type 2 cultures precultured at 1 μmol / l (P < 0.05).
Gestational protein restriction impairs insulin - regulated glucose transport mechanisms in gastrocnemius muscles of adult male offspring.
However, this increase in basal glucose transport under very high insulin concentrations seems to be explained by an increased GLUT1 expression (10).
Cartee GD, Kietzke EW, Briggs - Tung C. Adaptation of muscle glucose transport with caloric restriction in adult, middle - aged, and old rats.
Taken together, our data suggest that insulin resistance in patients with type 2 diabetes contain at least two important defects: a reduced glucose transport under basal conditions and a reduced GS activity under acute insulin stimulation, implicating a reduced glucose uptake in the fasting state and a diminished insulin - mediated storage of glucose as glycogen after a meal.
AKT is important for glucose transport into cells and for stopping glucose production in the liver.
Our data suggest that insulin resistance in patients with type 2 diabetes comprises at least two important defects under physiological insulin concentrations: a reduced glucose transport under basal conditions and a reduced GS activity under acute insulin stimulation, implicating a reduced glucose uptake in the fasting state and a diminished insulin - mediated storage of glucose as glycogen after a meal.
Glucose transport with brief dietary restriction: heterogenous responses in muscles.
ET or R - ALA individually increased insulin - mediated glucose transport activity in isolated epitrochlearis (44 - 48 %) and soleus (37 - 57 %) muscles.
Acute insulin stimulation increased glucose transport by 21 % in control cultures precultured at 1 pmol / l insulin, but at higher insulin concentrations we could not detect an effect of insulin on glucose uptake.
«Because these mice already process glucose efficiently, the actions of p75NTR on glucose transport indicate a direct role of this protein in the regulation of glucose metabolism.»
So, chromium will help you minimize insulin levels during the day and better glucose transport in the body and also provide energy.
Alpha - lipoic acid (ALA), a naturally occuring compound and a radical scavenger was shown to enhance glucose transport and utilization in different experimental and animal models.
The aim of the present study was to evaluate glucose transport and GS activity in human satellite cell cultures established from type 2 diabetic and control subjects.
We found a reduced intracellular glucose content, indicative for a lowered glucose transport activity, which is in agreement with our finding of a reduced basal glucose uptake in diabetic cultures.
However, Krutzfeldt et al. (8) could not show any differences in glucose transport between muscle cell cultures established from lean healthy first - degree relatives, and Jackson et al. (9) found a reduced insulin - stimulated glucose uptake in myoblast cultures from first - degree relatives, with some of these cultures expressing an increased basal glucose uptake.
To identify the rate - limiting step for glycogen synthesis in type 2 diabetic subjects compared with control subjects, the experimental system has to include at least two conditions: 1) similar extracellular conditions under which glucose transport / phosphorylation can be studied and 2) identical glucose uptake fluxes, which will allow the identification of downstream defects.
Another way you can blunt hunger is by feeling energetic and improving glucose transport in the body.
The decreased glucose transport in diabetic cultures will decrease the intracellular glucose and G6P content, but because the GS activity is also reduced, it is possible to obtain G6P concentrations that are nearly identical in control and type 2 diabetic cell cultures.
As we will discuss in some detail, Akt regulates glucose transport as well as glycogen synthase; but, as well as, it's actually a growth factor and can trigger also many growth pathways.
Since insulin is involved in more than just glucose transport and disposal, a strong case can be made that it may be healthier for a diabetic to use some insulin than to simply avoid foods that require it.
That's not too problematic for post workout nutrition, thanks to non-insulin-mediated glucose transport and increased insulin sensitivity within 30 min of exercise.
Fermentable dietary fiber increases GLP - 1 secretion and improves glucose homeostasis despite increased intestinal glucose transport capacity in healthy dogs
Meta Lipoate 300 provides alpha - lipoic acid to support glucose transport.
There is evidence to suggest that repeated hyperglycemia could induce a protective downregulation of blood - to - brain glucose transport, resulting in a lowered threshold for autonomic activation (38).
They then surmised that this change meant that the dog protein must be better at glucose transport.
Effect of preculturing human satellite cell cultures in increasing concentrations of insulin on the basal and insulin - stimulated glucose transport activity in cultures of human myofibers.
At the same time, the fasting group showed increased levels of a muscle protein that «is responsible for insulin - stimulated glucose transport in muscle and thus plays a pivotal role in regulation of insulin sensitivity,» Dr Hespel said.
Stimulation by 1,25 - dihydroxyvitamin D3 of insulin receptor expression and insulin responsiveness for glucose transport in U-937 human promonocytic cells
Whereas the improvement in insulin - mediated glucose transport in soleus due to R - ALA was associated with decreased protein carbonyl levels (an index of oxidative stress), improvement because of ET was associated with decreased protein carbonyls as well as enhanced GLUT - 4 protein.
Engagement of the Insulin - sensitive Pathway in the Stimulation of Glucose Transport by Alpha - lipoic Acid in 3T3 - L1 Adipocytes Diabetologia 2000 (Mar); 43 (3): 294 — 303 These results indicate that R (+) alpha - lipoic acid directly activates lipid, tyrosine and serine / threonine kinases in target cells, which could lead to the stimulation of glucose uptake induced by this natural cofactor.
In accordance, Jackson et al. (9) showed that preculturing at 0.1 μmol / l insulin decreased the effect of acute insulin stimulation on glucose transport.
Insulin resistance in skeletal muscle in vivo is associated with impaired glucose transport and glycogen synthesis (6,13,14).
ALA may protect tissues from free radicals, enhance glucose transport and metabolism, support nerve tissue health (especially peripheral nerves), enhance the production of cellular energy (ATP), and support liver health and detoxification.
To determine the relative importance of glucose transport and GS to insulin - stimulated muscle glucose metabolism, we measured the intracellular concentrations of glucose, G6P, and glycogen in cell cultures established from controls and subjects with type 2 diabetes.
Brief dietary restriction increases skeletal muscle glucose transport in old Fischer 344 rats.
High rT3 levels with low T3 levels lead to reduced glucose transport into cells and reduced glucose utilization throughout the body.