Sentences with phrase «high sequence»

The poor apparent coverage was the result of high sequence divergence of the TMAdV genome from SAdV - 18, which hindered the identification of most of the 16,524 actual deep sequencing reads derived from TMAdV (Fig. 2B, red).

«Multiple displacement technology uses an enzyme which has a very high processivity and is a really high - fidelity enzyme, so we can ensure uniform coverage during the process... and a very high sequence accuracy,» says Langsdorff.

It has a small genome (about 2 x Arabidopsis) with high sequence identity (average 92 %) with

MinION is able to produce very long reads (reads over 100 ~ kBp were reported), however it suffers from high sequencing error rate.

However, the high sequence divergence in the fiber protein (Table 2), as well as the absence of fiber motifs conserved among adenoviruses that bind CAR [36], [37](coxsackievirus - adenovirus receptor) or CD46 [38], [39], [40](data not shown), suggest that neither of these two human adenoviral receptors may be the attachment receptor for TMAdV.

In this regard, the high sequence divergence of TMAdV relative to the known human / simian adenoviruses (Fig. 3), and comparable sequence similarity in the polymerase gene to a porcine adenovirus (Figs. 3 and S1) are striking.

MRD testing simply requires additional cell equivalents of DNA to be sampled and a higher sequencing read depth.

This analysis was limited to sequence reads that mapped to the targeted chromosome X and Y SNPs with a mapping quality score of at least 37, where clusters of duplicate reads (as identified by orientation, and start and end position) were represented by the read with the highest sequence quality.