Sentences with phrase «hypoxic regions»
"Hypoxic regions" refer to areas in the body or the environment that have low levels of oxygen. Full definition
«The IMM teams showed clearly that the gene was switched on only in hypoxic regions,» says Sue Kingsman, the research director of Oxford BioMedica.
newscientist.com
One percent oxygen was used to represent hypoxia, although levels of oxygen will also vary within hypoxic regions of tumors.
Consequently, they discovered that by blocking Nrp1, macrophages were no longer able to migrate inside hypoxic regions in the tumor.
Farmland runoff containing fertilizers and livestock waste is the main source of the nitrogen and phosphorus nutrients that cause the annual Chesapeake Bay hypoxic region, which is also known as a dead zone.
The irregular vasculature of solid tumors creates hypoxic regions, which are characterized by cyclic periods of hypoxia and reoxygenation.
Importantly, NSCs can target breast cancer metastasis in the brain [9] and can penetrate deep and hypoxic regions of solid tumors [7].
When oxygen is scarce, however, HIF - 1α starts to accumulate and turns on the expression of a host of genes that assist in promoting and increasing oxygen delivery to hypoxic regions.