Sentences with phrase «immune recognition»

This new marker of senescent cells is recognized by a naturally occurring IgM antibody that belongs to the innate immune system and is likely to be involved in a natural mechanism of immune recognition and clearance of senescent cells.

The laboratory focuses on understanding the mechanism of peptide selection for immune recognition by major histocompatibility complex (MHC) molecules.

«It is apparent from these data that B. burgdorferi bacteria, which have had time to adapt to their host, have the ability to escape immune recognition, tolerate the antibiotic doxycycline and invade vital organs such as the brain and heart,» said lead author Monica Embers, PhD, assistant professor of microbiology and immunology at Tulane University School of Medicine.

The current efforts of her laboratory are focused primarily on four areas of innate immunity: the molecular basis of pathogen recognition; innate immunity to malaria; Type I interferon gene regulation; and counter regulation of innate immune recognition.

«Rosetta Stone» to decode immune recognition.»

Furthermore, the T cells can recognize PDPN on the tumor surface even with the absence of the body's own immune recognition system, which is usually compromised in cancer.

«These mechanisms block immune recognition cells from entering.

The biology is however very interesting with implications for the evolution of both cancer cell clones and immune recognition within and between species.»

Specifically, some tumor cells appeared to express PD - L1, essentially «wrapping» themselves in it to avoid immune recognition and destruction.

Collectively, their work has elucidated foundational mechanisms in cancer's ability to evade immune recognition and, in doing so, has profoundly altered the understanding of disease development and treatment.

Scientists have identified several ovarian cancer - associated antigens — molecules on or in cells that are capable of eliciting an immune response — that can serve as targets for immune recognition and attack.

«That has hampered not only understanding of immune recognition but also our ability to use the immune system more effectively to target new viruses or mutations driving tumor cells,» Thomas said.

Innate immune recognition and response to cell death Kenneth RockUniversity of Massachusetts, USA 19th March 201804:15 pm Host: Falko Apel, MPIIB, Berlin Location: Max Planck Institute for Infection Biology, Seminar room 1/2 - Campus Charité Mitte

The expansion of gene families related to immune recognition, endocytosis and caspase - mediated apoptosis indicates the mussel's adaptation to the presence of chemoautotrophic endosymbionts in its gills.

The results may open up new therapeutic avenues for the treatment of malignant melanoma, demonstrate a new type of immune recognition and could even shed new light onto the incipient events causing the development of vitiligo.

«For instance, efforts to block the infection - enhancing activity of these semen amyloids for STD prevention must now consider the potential effects of such interventions on sperm quality and immune recognition of male antigens.»

He maintains an active research program focused on understanding the mechanisms of immune recognition and tolerance in ovarian cancer, as well as the translation of the findings to clinical immunotherapy trials.

This position, funded by Cancer Research UK, will explore whether manipulation of a novel antigen presentation checkpoint can enhance the repertoire of tumour antigens presented for immune recognition.